# OpenEpi, Version of December 2003

## Test Results for DoseResponse Module

Dataset # | Left Side | Data | Compared with | Result
DoseResp1 a | Exposure 0,1,2 | Stratum 1 1,131 1,104 4,51 Stratum 2 0,188 6,152 15,83 Stratum 3 3,161 12,130 22,65 Stratum 4 11,169 21,134 39,68 Stratum 5 23,157 42,97 34,52 | Schlesselman, JJ Case-Control Studies, 1982, 205. Cigarette smoking among Female Cases of Myocardial Infarction and Controls, stratified in 5 age groups. | Mantel-Haenszel extended test for trend agreed perfectly until continuity correction was added per Rosner (see below) MH odds ratios at two levels of smokers vs. baseline non-smokers also agree. Results will now differ slightly because of the correction.
DoseResp1 b | Exposure 0,1,2 | 1,131,1,104 0,188,6,152 3,161,12,130 11,169,21,134 23,157,42,97 | Epi Info, Statcalc, the DOS program, 1993 | Mantel-Haenszel extended test for trend agreed perfectly until continuity correction was added per Rosner (see below) MH odds ratios at two levels of smokers vs. baseline non-smokers also agree.
DoseResp2 | Exposure 1,2,3 | Women Cases, Controls 196,603, 223,486 103,232 Men Cases, Controls 188,348 313,383 232,206 | Rosner, B. Fundamentals of Biostatistics, Duxbury, 2000. | After adding the continuity correction employed by Rosner, the Mantel extended test (with cc) agrees perfectly.

Testing by Andy Dean, using materials listed.

Conclusion: Module is ready for use, although users are advised to confirm important results with at least one other software module.