## Matched Pair Case-Control Study

Single Table Analysis
|  | Controls
|  | (+) | (-)
| (+) | 3 | 7 | 10
Cases | (-) | 1 | 9 | 10
|  | 4 | 16 | 20

Measures of Association
| P Values
| Test | Value | d.f. | 1-tail | 2-tail
| McNemar: | 4.5 | 1 |  | 0.03389
| McNemar with continuity correction: | 3.125 | 1 |  | 0.07710
| Fisher exact |  | 0.03516 | 0.07031
| Mid-P exact |  | 0.01953 | 0.03906
| There are 8 discordant pairs.
| Because this number is fewer than 20, it is recommended that only the exact results be used.
Odds-based Estimates
| 95% Confidence Intervals
| Parameter | Point Estimate | Lower,Upper | Type
| Pair-Matched Odds Ratio: | 7 | 0.8614, 56.89¹ | Taylor series
| CMLE Odds Ratio* | 7 | 1.082, 159¹ | Mid-P Exact
|  |  | 0.8993, 315.5¹ | Fisher Exact
*Conditional maximum likelihood estimate of Odds Ratio
(P)indicates a one-tail P-value for Protective or negative association; otherwise one-tailed exact P-values are for a positive association. Martin,D; Austin,H (1991) An efficient program for computing conditional maximum likelihood estimates and exact confidence limits for a common odds ratio. Epidemiology 2, 359-362.

### Results from OpenEpi, Version 2, open source calculator--MatchCC

file:///C:/NextOpenEpi/MatchCC/MatchCC.htm
Source file last modified on 11/08/2007 20:34:03
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